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ElmiGone™ (120) | 15705

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Quick Overview

ElmiGone™ is an exclusive herbal formula by Santegra®.  The powerful ingredients of the formula work synergistically  to provide effective antiparasitic and antihelmintic action.


The product has been manufactured using high quality pure herbs and the technology that ensures all their beneficial properties intact, in strict compliance with GMP and TÜV regulations.

ElmiGone™ (120)

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ElmiGone™ is an exclusive herbal formula by Santegra® with antiparasitic and antihelmintic properties.

According to the International Health Organization one quarter of our planet’s population is suffering from parasitic infections. There are plenty of sources of parasitic infections around us; the most common ones come from the water and food supply, and the pets. Parasites live and feed off the host. They can deprive us of vitamins, nutrients, and decrease our energy levels. Their waste is toxic. That is why it is so important to get rid of these unwelcome guests, and protect our bodies.

ElmiGone™ contains well-known herbs with antiparasitic and antihelmintic properties, such as black walnut, pumpkin seeds, and garlic.

Traditionally black walnut has been used as an antiseptic, antiparasitic, and a laxative, helping rid the body of intestinal parasites and tapeworms, reducing constipation, and healing skin conditions.
Black walnut hull improve digestion and food assimilation, decrease colic severity, heartburn, flatulence, and stimulate the bile-expelling function.
Pumpkin seeds are one of the most effective and safe antihelmintic products, especially against different kinds of tapeworms. Pumpkin seeds contain cucurbitine - rare amino acid with antihelmintic properties that has no side effects (do not cause bowel irritations or intoxication), and can be used for children, pregnant women, and seniors.
Clove is a strong antiseptic, germicide and preservative. It is used to destroy tapeworm and parasitic eggs.
Sage, knotweed, chamomile and fennel have disinfectant and anti-inflammatory properties.
Gentian root, thyme leaf, peppermint leaf, and black pepper fruit have positive effect on the gastrointestinal tract.
Fenugreek seed has mild laxative action.
Chlorophyll stimulates intestinal activity, eliminates mouth odor, and detoxifies the body.
ElmiGone™ is an effective treatment against parasites. For the best results, use ElmiGone™ twice a year preferably in combination with FortiFi™ that cleanses the intestines naturally.

ElmiGone™ has many other beneficial properties: promotes wound healing, strengthens the gums, and decreases gingival hemorrhage, helps with the inflammation of hemorrhoids and hemorrhoidal bleeding.

Name ElmiGone™ (120)
Product Line Esenza

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Usage

As a dietary supplement take 2 capsules daily in the morning for the first 10 days, then 4-5 capsules daily for the next 20 days, with a big glass of water on an empty stomach.


Contraindication

Individual intolerance, stomach ulcer, thyrotoxicosis.


Proprietary Blend - 390.0 mg: Black Walnut (Juglans regia) hull, Pumpkin (Cucurbita maxima) seed, Knotweed (Polygonum cuspidatum) 10:1 extract, Clove (Eugenia caryophyllata) bud, Sage (Salvia officinalis) leaf, Garlic (Allium sativum L.) bulb, Gentian (Gentiana lutea L.) root, Fenugreek (Trigonella foenum-graecum L.) seed, Chamomile (Anthemis nobilis (LINN.)) 10:1 flower extract, Black pepper (Piper nigrum (LINN.)) fruit, Peppermint (Mentha piperita L). leaf, Thyme (Thymus vulgaris L.) leaf, Fennel (Foeniculum vulgaris L.) seed, Sodium copper chlorophyllin.

The active constituent of black walnut is juglone, which has demonstrated both antiparasitic and antimicrobial activity. (3)

A decoction of the hull of Juglans nigra fruit has been used traditionally to expel worms. (4) The unripe hulls of Juglans nigra contain 1,4-naphthoquinones including juglone and plumbagin. (5) The juglone content in hulls varies with different cultivars and different months of growth. (6)

In vitro studies indicate that plumbagin inhibited the motility of and hatching of Haemonchus contortus first stage larvae.

Plumbagin was larvacidal towards Ascaris suum at the highest test concentration (100 mM). Partial inhibition of embryonic development of A. suum occurred with plumbagin. The authors suggested that because of the relatively high doses required for the maximal effect on inhibiting the development of larval stages, plumbagin may not find practical application. The combination with other anthelmintic herbs would however, boost the activity of plumbagin. (6)

Garlic is mentioned in the Bible and the Talmud. Hippocrates, Galen, Pliny the Elder, and Dioscorides all mention the use of garlic for many conditions, including parasites, respiratory problems, poor digestion, and low energy. Its use in China was first mentioned in A.D. 510. Louis Pasteur studied the antibacterial action of garlic in 1858.

Garlic has been demonstrated to kill parasites, including amoeba (7) and hookworm (8) in test tubes and in animals. Older studies in humans support the use of garlic to treat roundworm, pinworm, and hookworm. (9)

Garlic (Allium sativum) has been used as an anthelmintic in western herbal medicine, for example, as a decoction or freshly mashed and administered to children on an empty stomach. (10)

Garlic extract was effective against Rhabditis spp. and the eggs of Ascaris suum in vitro. (11)

The pharmacological properties of essential oils obtained from two varieties of Anthemis nobilis was studied. The two varieties, named "white-headed" or double flowered and "yellow-headed", present considerable morphological differences and yield essential oils with different composition. These essential oils proved to possess interesting anti-inflammatory and sedative properties, especially that derived from the "White-headed" variety. (12)

The present study investigates the hepatoprotective effect of fenugreek seed polyphenolic extract (FPEt) against ethanol-induced hepatic injury and apoptosis in rats. Chronic ethanol administration (6 g/kg/day x 60 days) caused liver damage that was manifested by the elevation of markers of liver dysfunction--aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), lactate dehydrogenase (LDH), bilirubin and gamma-glutamyl transferase (GGT) in plasma and reduction in liver glycogen. The effects on alcohol metabolizing enzymes such as alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) were studied and found to be altered in the alcohol-treated group. Ethanol administration resulted in adaptive induction of the activities of cytochrome p450 (cyt-p-450) and cytochrome-b5 (cyt-b5) and reduction in cytochrome-c-reductase (cyt-c-red) and glutathione-S-tranferase (GST), a phase II enzyme. Further, ethanol reduced the viability of isolated hepatocytes (ex vivo) as assessed by the trypan blue exclusion test and increased hepatocyte apoptosis as assessed by propidium iodide staining (PI). Treatment with FPEt restored the levels of markers of liver injury and mitigated the alterations in alcohol metabolizing and detoxification enzymes and the electron transport component cytochrome-c reductase. Increased hepatocyte viability and reduced apoptotic nuclei were observed in FPEt-treated rats. These findings demonstrate that FPEt acts as a protective agent against ethanol-induced abnormalities in the liver. The effects of FPEt are comparable with those of a known hepatoprotective agent, silymarin. (13)

The insecticidal activity of Trigonella foenum-graecunm (fenugreek) against the larval maturation and adult emergency of An. pharoensis 3rd stage was evaluated under controlled laboratory conditions. Concentrations of 100%, 70%, 50%, 25%, 5%, 2%, 1%, 0.9%, 0.7%, 0.5% & 0.3% showed 100% larval mortality rate. 0.2% & 0.1% caused mortality of 88.9% & 66.7% respectively. On the other hand, the fecundity of emerged adults was zero % and 33.3%. However, one control larvae died and the nine emerged adults were fertile. So, it was recommended to be use in controlling larvae of An. pharoensis. (14)

The present study describes the antimicrobial activity and free radical scavenging capacity (RSC) of essential oils from Mentha aquatica L., Mentha longifolia L., and Mentha piperita L. The chemical profile of each essential oil was determined by GC-MS and TLC. All essential oils exhibited very strong antibacterial activity, in particularly against Esherichia coli strains. The most powerful was M. piperita essential oil, especially towards multiresistant strain of Shigella sonei and Micrococcus flavus ATTC 10,240. All tested oils showed significant fungistatic and fungicidal activity [expressed as minimal inhibitory concentration (MIC) and minimal fungicidal concentration (MFC) values, respectively], that were considerably higher than those of the commercial fungicide bifonazole. The essential oils of M. piperita and M. longifolia were found to be more active than the essential oil of M. aquatica. Especially low MIC (4 microL/mL) and MFC (4 microL/mL) were found with M. piperita oil against Trichophyton tonsurans and Candida albicans (both 8 microL/mL). The RSC was evaluated by measuring the scavenging activity of the essential oils on the 2,2-diphenyl-1-picrylhydrazyl (DPPH) and OH radicals. All examined essential oils were able to reduce DPPH radicals into the neutral DPPH-H form, and this activity was dose-dependent. However, only the M. piperita oil reduced DPPH to 50 % (IC50 = 2.53 microg/mL). The M. piperita essential oil also exhibited the highest OH radical scavenging activity, reducing OH radical generation in the Fenton reaction by 24 % (pure oil). According to GC-MS and TLC (dot-blot techniques), the most powerful scavenging compounds were monoterpene ketones (menthone and isomenthone) in the essential oils of M. longifolia and M. piperita and 1,8-cineole in the oil of M. aquatica. (15)

The essential oil extracted from the dried flower buds of clove, Eugenia caryophyllata L. Merr. & Perry (Myrtaceae), is used as a topical application to relieve pain and to promote healing and also finds use in the fragrance and flavouring industries. The main constituents of the essential oil are phenylpropanoids such as carvacrol, thymol, eugenol and cinnamaldehyde. The biological activity of Eugenia caryophyllata has been investigated on several microorganisms and parasites, including pathogenic bacteria, Herpes simplex and hepatitis C viruses. In addition to its antimicrobial, antioxidant, antifungal and antiviral activity, clove essential oil possesses antiinflammatory, cytotoxic, insect repellent and anaesthetic properties. This short review addresses the chemical composition and biological effects of clove essential oil, and includes new results from GC/MS analysis and a study of its antimicrobial activity against a large number of multi-resistant Staphylococcus epidermidis isolated from dialysis biomaterials. (16)

Many essential oils are known to possess an antioxidant activity and antifungal properties and therefore they potentially act as antimycotic agents. Essential oil of clove (Eugenia caryophyllata) was isolated by hydrodistillation. The chemical composition of the essential oil was analysed by gas chromatography and gas chromatography/mass spectroscopy. The antioxidant effect of the tested oil was evaluated by measuring its 2,2-diphenyl-l-1-picrylhydrazil radical scavenging ability and the antiradical dose required to cause a 50% inhibition (IC50) was recorded. The antifungal activity of essential oils was evaluated against 53 human pathogenic yeasts using a disc paper diffusion method. Our results show that the major components present in the clove bund oil were eugenol (88.6%), eugenyl acetate (5.6%), beta-caryophyllene (1.4%) and 2-heptanone (0.9%). The tested essential oil exhibited a very strong radical scavenging activity (IC50 = 0.2 microg ml-1) when compared with the synthetic antioxidant (tert-butylated hydroxytoluene, IC50 = 11.5 microg ml-1). On the other hand, this species displayed an important antifungal effect against the tested strains. It is clear that clove oil shows powerful antifungal activity; and it can be used as an easily accessible source of natural antioxidants and in pharmaceutical applications. (17)

The essential oils of rosemary (Rosmarinus officinalis L.) and sage (Salvia officinalis L.) were analyzed by means of gas chromatography-mass spectrometry and assayed for their antimicrobial and antioxidant activities. Antimicrobial activity was tested against 13 bacterial strains and 6 fungi, including Candida albicans and 5 dermatomycetes. The most important antibacterial activity of both essential oils was expressed on Escherichia coli, Salmonella typhi, S. enteritidis, and Shigella sonei. A significant rate of antifungal activity, especially of essential oil of rosemary, was also exhibited. Antioxidant activity was evaluated as a free radical scavenging capacity (RSC), together with the effect on lipid peroxidation (LP). RSC was assessed by measuring the scavenging activity of essential oils on 2,2-diphenyl-1-picrylhydrazil (DPPH) and hydroxyl radicals. Effects on LP were evaluated following the activities of essential oils in Fe(2+)/ascorbate and Fe(2+)/H2O2 systems of induction. Investigated essential oils reduced the DPPH radical formation (IC50 = 3.82 microg/mL for rosemary and 1.78 microg/mL for sage) in a dose-dependent manner. Strong inhibition of LP in both systems of induction was especially observed for the essential oil of rosemary. (18)

Experimental research was carried out at the Parasitology and Chemistry laboratories of the Jorge Basadre Grohmann National University, in Tacna. The process involved two phases: (1) determination of the minimum inhibitory concentration (MIC) of Cucurbita Maxima as an antiparasitic agent using canine tapeworms with an intestinal isolation of 5 to 6 hours, and (2) determination of the side-effects of Curbita Maxima on exposed albino rats. It was found that the MIC of 23 gr. of pumpkin seed in 100 ml. of distilled water can produce an antihelminthic effect. This concentration is equivalent to +/- 73 pumpkin seeds (x2 = 5.6, p 23 gr. There is a protheolithic effect with an average survival time of 38.4 minutes.Microscopically the mature proglottids present a destruction of the tegument involving the basal membrane. In the gravid proglottids there is egg destruction. These findings are accentuated when experimenting with Cucurbita Maxima in a concentration of 30 and 32 gr. Superficial non-erosive gastritis was found in weys rats after 4 hours of administering 9 gr/kg. (19)

Piper nigrum finds an extensive application in antibacterial preparations belonging to Ayurvedic system of medicine. A bioguided extraction and fractionation of the petroleum ether extract of the berries of P. nigrum afforded 2E, 4E, 8Z-N-isobutyleicosatrienamide (1), pellitorine (2), trachyone (3), pergumidiene (4) and isopiperolein B (5). Pergumidiene and trachyone are isolated for the first time from P. nigrum. All the isolated compounds were active against Bacillus subtilis, Bacillus sphaericus, and Staphylococcus aureus amongst Gram + ve bacteria, and Klebsiella aerogenes and Chromobacterium violaceum among Gram -ve bacterial strains. (20)

The volatile oils of black pepper [Piper nigrum L. (Piperaceae)], clove [Syzygium aromaticum (L.) Merr. & Perry (Myrtaceae)], geranium [Pelargonium graveolens L'Herit (Geraniaceae)], nutmeg [Myristica fragrans Houtt. (Myristicaceae), oregano [Origanum vulgare ssp. hirtum (Link) Letsw. (Lamiaceae)] and thyme [Thymus vulgaris L. (Lamiaceae)] were assessed for antibacterial activity against 25 different genera of bacteria. These included animal and plant pathogens, food poisoning and spoilage bacteria. The volatile oils exhibited considerable inhibitory effects against all the organisms under test while their major components demonstrated various degrees of growth inhibition. (21)

Institute for Biological Research, "S. Stankovic," Bulevar despota Stefana, Belgrade, Serbia.

The in vivo evaluation of the toxicological and antifungal activity of the essential oil of Thymus vulgaris L. and its main component thymol was made on 2-month-old male Wistar rats. We examined the therapeutic potency against experimentally induced dermatomycoses in rats, using the most frequent dermatomycetes, Trichophyton mentagrophytes, T. rubrum, and T. tonsurans. The therapeutic efficacy of a 1% solution of the essential oil of Thymus vulgaris and thymol as well as the commercial preparation bifonazole was evaluated. During the 37-day observation period the oil-treated animals were cured. (22)

A parasite is a living being or organism that exists by depending on another organism. Parasites that infect humans are much more widespread than many of us realize. Parasitic diseases affect not only poverty-stricken peoples in remote areas of the world, but they also can be important health problems for rich and poor throughout the world. (1)

Parasites thrive within your body, affecting various tissues and organs, and often without your realizing it. In fact, parasitic infection frequently is undiagnosed because symptoms can be confused with a variety of conditions and diseases. But as parasites steal your nutrients and feed off your cells, they damage your body.

According to Ann Louise Gittleman, nutritionist and author of "Guess What Came to Dinner," there are six ways parasites can harm you. They can:

  • Destroy cells faster than your body can regenerate them;

  • Produce toxic substances, causing chronic infection;

  • Irritate tissues, which causes inflammation;

  • Penetrate the skin (causing dermatitis), and perforate and damage your intestinal lining;

  • Cause obstruction of the intestine and produce pressure on other organs, including the brain and heart;

  • Depress your immune system while at the same time activating your immune response, which can result in immune system exhaustion. (2)

Human body can be a host to about 100 different kinds of parasites – from microscopic amebas to several meters long worms. Parasites could be found not only in the intestines, but in any other part of the body: lungs, liver, muscles, brain, blood and even eyes!
Parasites can create such health problems as diarrhea, gastrointestinal upset, joint and muscle aches, suppressed immunity, skin problems, irritability, sleep disturbances, tooth-grinding during sleep, respiratory inflammation, and tumors.

Parasitic infection can cause both weight gain and weight loss.

Do you have an illness you just can't seem to shake off? Are you chronically tired or lethargic? Do you have a vague feeling of ill health that can't be identified? You might assume it's the flu, or that you're simply in need of more rest. And while that may be the case, these symptoms can indicate a parasitic infection. The problem, says author Gittleman, is that many physicians "hardly ever suspect parasites as a current health problem," and so symptoms are attributed to any number of other diseases. And if parasite infection is not treated, these unwelcome guests can remain in your system for decades. (2)

"Since most of us eat three times a day and drink water frequently throughout the day, our exposure to these sources is constant," says Gittleman. Most food-borne parasites are from undercooked meats and fish. It is recommended to use a meat thermometer to check the internal temperature, and it's important to refrain from sampling a dish before it's thoroughly cooked.

But it's not just eating food that causes problems; parasites can be transmitted during food preparation. Cutting boards and other food preparation surfaces, as well as utensils used in food preparation, should be disinfected after each use. (2)

One of the best ways to rid your body of parasites is to "cleanse" it. Herbs traditionally have been used to cleanse and strengthen your body's systems, especially effective are supplements that contain a number of herbs known to promote cleansing.

1. Parasitic Roundworm Diseases, NIAID Fact Sheet: NIAID
2. Ann Louise Gittleman Ph. D., CNS, Guess What Came to Dinner: Parasites and Your Health.
3. Chevallier A. The Encyclopedia of Medicinal Plants . London, England: DK Publishing, 1996:222-23.
4. Felter HW, Lloyd JU, King's American Dispensatory. 18th Ed, 3rd revision, volume 1. First published 1905, reprinted Eclectic Medical Publications, Portland, 1983.
5. Binder RG, Benson ME, Flath RA. Phytochem 1989; 28(10): 2799-2801
6. Fetterer RH, Fleming MW. Comp Biochem Physiol C 1991; 100(3): 539-342.
7. Mirelman D, Monheit D, Varon S. Inhibition of growth of Entamoeba histolytica by allicin, the active principle of garlic extract (Allium sativum). J Infect Dis 1987;156:243–4.
8. Bastidas CJ. Effect of ingested garlic on Necator americanus and Ancylostoma caninum. Am J Trop Med Hyg 1969;13:920–3.
9. Koch HP, Lawson LD, eds. Garlic: The Science and Therapeutic Application of Allium sativum L. and Related Species. Baltimore: Williams & Wilkins, 1996, 173–4.
10. Guarrera PM. J Ethnopharmacol 1999; 66(1-3): 183-192.
11. Chybowski J. Herbal Pal 1997; 43(4): 383-387.
12. Rossi T, Melegari M, Bianchi A, Albasini A, Vampa G. Sedative, anti-inflammatory and anti-diuretic effects induced in rats by essential oils of varieties of Anthemis nobilis: a comparative study. Pharmacol Res Commun. 1988 Dec;20 Suppl 5:71-4
13. Kaviarasan S, Anuradha CV. Fenugreek (Trigonella foenum graecum) seed polyphenols protect liver from alcohol toxicity: a role on hepatic detoxification system and apoptosis. Pharmazie. 2007 Apr;62(4):299-304
14. Abdel Halim AS. Efficacy of Trigonella foenum-graecum on third stage larvae and adult fecundity of Anopheles pharoensis. J Egypt Soc Parasitol. 2006 Aug;36(2):397-404
15. Mimica-Dukić N, Bozin B, Soković M, Mihajlović B, Matavulj M. Antimicrobial and antioxidant activities of three Mentha species essential oils. Planta Med. 2003 May;69(5):413-9
16. Chaieb K, Hajlaoui H, Zmantar T, Kahla-Nakbi AB, Rouabhia M, Mahdouani K, Bakhrouf A. The chemical composition and biological activity of clove essential oil, Eugenia caryophyllata (Syzigium aromaticum L. Myrtaceae): a short review. Phytother Res. 2007 Jun;21(6):501-6
17. Chaieb K, Zmantar T, Ksouri R, Hajlaoui H, Mahdouani K, Abdelly C, Bakhrouf A. Antioxidant properties of the essential oil of Eugenia caryophyllata and its antifungal activity against a large number of clinical Candida species. Mycoses. 2007 Sep;50(5):403-6.
18. Bozin B, Mimica-Dukic N, Samojlik I, Jovin E. Antimicrobial and antioxidant properties of rosemary and sage (Rosmarinus officinalis L. and Salvia officinalis L., Lamiaceae) essential oils. J Agric Food Chem. 2007 Sep 19;55(19):7879-85. Epub 2007 Aug 21
19. Díaz Obregón D, Lloja Lozano L, Carbajal Zúñiga V. Preclinical studies of cucurbita maxima (pumpkin seeds) a traditional intestinal antiparasitic in rural urban areas. Rev Gastroenterol Peru. 2004 Oct-Dec;24(4):323-7
20. Reddy SV, Srinivas PV, Praveen B, Kishore KH, Raju BC, Murthy US, Rao JM. Antibacterial constituents from the berries of Piper nigrum. Phytomedicine. 2004 Nov;11(7-8):697-700.
21. Dorman HJ, Deans SG. Antimicrobial agents from plants: antibacterial activity of plant volatile oils. J Appl Microbiol. 2000 Feb;88(2):308-16.
22. Sokovic M, Glamoclija J, Ciric A, Kataranovski D, Marin PD, Vukojevic J, Brkic D. Antifungal Activity of the Essential oil of Thymus vulgaris L. and Thymol on Experimentally Induced Dermatomycoses. Drug Dev Ind Pharm. 2008 Jul 24:1-6. [Epub ahead of print]


 

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