Refungin™ (90)

In stock
SKU
419

Refungin™ contains natural beta-carotene, natural form of vitamin E, the most bioavailable form of selenium (Selenium + GPM™), Pau d’Arco bark 4:1 extract, Echinacea purpurea 5:1 extract (aerial parts), standardized garlic extract.

The product has been manufactured using high quality pure raw materials and the technology that ensures all their beneficial properties intact, in strict compliance with GMP and TÜV regulations.

Many of us believe that our modern life conditions and personal hygiene products are keeping us protected against different kinds of parasites. We are used to think that these disgusting creatures live only in exotic or undeveloped countries. Unfortunately it is not true. According to World Health Organization more than 2 billion people in the world (mostly children) are suffering from parasitic infections.

How do you think parasites get into the body? Actually much easier than you can even imagine: if you swim in stagnant water, drink tap water, use tap water to rinse contact lenses, have pets, if you like to walk barefoot, and in many others cases you may become infected with parasites.

When the immune system is week, fungus (such as the yeast-like fungus Candida albicans) can start to multiply and can cause serious illnesses. Candida albicans is a yeast or fungus which is normally present in small amounts in the human body. However, it can multiply very rapidly under various conditions.

Unbalanced diet, overconsumption of sugar, milk and meat products, alcoholic intoxication, antibiotics, and stress can provoke uncontrollable fungus reproduction.

Candidosis weakens the immune system; its symptoms may be mistaken for colitis, cystitis, gastritis, or many other diseases that makes it harder for the treatment.

Do you have an illness you just can't shake off? Are you chronically tired or lethargic? Do you have a vague feeling of ill health that can't be identified? You might assume it's the flu, or that you're simply in need of more rest. But it is quite possible that you have parasitic invasion, and if it is not treated, these unwelcome guests can remain in your system for decades.

How parasites can harm you?

  • weaken your immune system;

  • produce toxic substances, causing chronic infection;

  • destroy cells faster than your body can regenerate them;

  • cause inflammation processes.

To get rid of parasites, you need to “cleanse” the body.
Refungin™ is an effective natural Santegra®’s product that provides antifungal, antiparasitic and antihelminthic action, and helps to eliminate different toxins from the body.

Refungin™ contains:

Pau d’Arco (Tabebuia impetiginosa) bark extract provides antifungal and antiparasitic activity, strengthens the immune system.

Garlic (Allium sativum L.) is a powerful antimicrobial agent, effective against many different kinds of parasites.

Black walnut (Juglans regia) bark is an effective antihelmintic and antiparasitic remedy.

Echinacea (Echinacea purpurea) extract is known as a wonderful immune system stimulator.

Borage seed (Borago officinalis) is rich in gamma-linoleic acid that belongs to omega-6 polyunsaturated acids, essential for normal metabolism.
Peppermint leaf (Mentha piperita) provides antiseptic, anti-inflammatory, and anti-bacterial action, improves digestion, contains essential oils, organic acids, tannins, and vitamins.
Caprylic acid has antimicrobial, antifungal effect, helps to support intestinal microorganism balance.
Refungin™ is not only cleansing the body, but also helps to restore the normal microflora, and the growth of “friendly” bacteria in the intestines.

Refungin™ contains vitamins-antioxidants A and E, which protect the body from free radical damage, support the immune system.

Selenium is powerful antioxidant, increases host defenses.

Warning: At the beginning of taking Refungin™ you can experience nausea and dizziness. These symptoms are caused by pathogenic organisms being destroyed and removed from the body, and will disappear as soon as the parasites are eradicated.

Per one capsule:

Vitamin A (as beta carotene) - 3 000 IU,
Vitamin E (as d-alpha-tocopheryl succinate) - 90 IU,
Selenium (as selenium + GPM) – 30 mcg;
Proprietary blend – 308 mg: Pau d’Arco (Tabebuia impetiginosa)  bark 4:1 extract, Echinacea (Echinacea purpurea) 5:1 extract (aerial parts),
Caprylic acid (as sodium caprylate),
Odor-controlled garlic (Allium sativum L.) extract (10,000 ppm allicin),
Black walnut (Juglans regia) bark ,
Peppermint leaf (Mentha piperita),
Borage seed (Borago officinalis)(10% GLA).

As a dietary supplement take 2 capsules 3 times a day, with a large glass of water.

 

Contraindication

Individual intolerance. 

 

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Lapachol has been used as a topical barrier to trematodes specifically Shcistosoma mansion, which causes schistosomiasis. This parasite lives in water and enters the host by penetrating through the skin. This pathogen can cause a complicated disease, which can sometimes be fatal. Also it is stated that oral lapachol formulation to be effective against skin penetration. In addition, lapachol is claimed to have some effect against Trypanosoma cruzi, which causes trypanosomiasis or Chaga’s disease. (1)

The biological activities of the naphthoquinones lapachol and its cyclization product beta-lapachone, extracted from trees of the genus Tabebuia, have been intensively studied. Given continuity to the studies about heterocyclic derivatives obtained from the reaction of these naphtoquinones with amino-containing reagents, 22 derivatives of beta-lapachone, nor-beta-lapachone and lapachol were synthesised and their activities against trypomastigote forms of T. cruzi were evaluated. The compounds were grouped as oxazolic, imidazolic, phenoxazinic, indolic, pyranic and cyclopentenic derivatives. The variability of the new structures is based on the great electrophilicity of 1,2-quinoidal carbonyls towards reagents containing nitrogen or carbon as nucleophilic centres. In relation to the trypanocidal activity of the synthesised compounds, in view of their structural diversity, tendencies only could be verified. Among the cyclofunctionalised products the oxazolic and imidazolic derivatives showed +/- 1.5 to 34.8 times higher activity than crystal violet, the standard drug for the sterilization of stored blood. These results corroborate the tendency of trypanocidal activity in imidazolic skeletons, and indicate that this moiety could be used as a guide for architectural delineation of molecules with potential value for the chemotherapy of Chagas disease. (2)

The active constituent of black walnut is juglone, which has demonstrated both antiparasitic and antimicrobial activity. (3)

A decoction of the hull of Juglans nigra fruit has been used traditionally to expel worms. (4)
The unripe hulls of Juglans nigra contain 1,4-naphthoquinones including juglone and plumbagin. (5)

The juglone content in hulls varies with different cultivars and different months of growth. (6) In vitro studies indicate that plumbagin inhibited the motility of and hatching of Haemonchus contortus first stage larvae. Plumbagin was larvacidal towards Ascaris suum at the highest test concentration (100 mM). Partial inhibition of embryonic development of A. suum occurred with plumbagin. The authors suggested that because of the relatively high doses required for the maximal effect on inhibiting the development of larval stages, plumbagin may not find practical application. The combination with other anthelmintic herbs would however, boost the activity of plumbagin. (6)

Garlic is mentioned in the Bible and the Talmud. Hippocrates, Galen, Pliny the Elder, and Dioscorides all mention the use of garlic for many conditions, including parasites, respiratory problems, poor digestion, and low energy. Its use in China was first mentioned in A.D. 510. Louis Pasteur studied the antibacterial action of garlic in 1858.

Garlic has been demonstrated to kill parasites, including amoeba (7) and hookworm (8) in test tubes and in animals. Older studies in humans support the use of garlic to treat roundworm, pinworm, and hookworm. (9)

Garlic (Allium sativum) has been used as an anthelmintic in western herbal medicine, for example, as a decoction or freshly mashed and administered to children on an empty stomach. (10) Garlic extract was effective against Rhabditis spp. and the eggs of Ascaris suum in vitro. (11)

Curled mint (Mentha crispa) leaf, a close relative of peppermint, has been shown in a preliminary trial to help relieve the symptoms of giardia and amoeba infections in children and adults, as well as to eliminate these parasites in many cases. (12) This study used a tincture of curled mint in the amount of 2 ml three times per day for five days, or 1 ml three times per day for five days for children. Given their close relationship, peppermint could probably be substituted for curled mint when curled mint is unavailable.

Echinacea is well known for its ability to stimulate the immune system, with such claims based on numerous scientific studies. The various actions of this herb may contribute to increasing the body’s resistance to bacterial and viral infection. A key constituent has demonstrated good effects against Candida, as well as the Leishmania and Listeria parasites in test tube and animal studies.

Preliminary research from the 1940s and 1950s indicated that caprylic acid (a naturally occurring fatty acid) was an effective antifungal compound against Candida infections of the intestines. (13, 14)

Caprylic acid inhibits fungal growth, and has been used to reduce Candida overgrowth in the GI tract. It’s strong effect on the immune system is reported in The American Journal of Clinical Nutrition.

Human body, due to unique immune defense system can withstand different kinds of infections. But there are some factors that can weaken the immune system: unbalanced diet, environmental pollution, medication (especially antibiotics). It can be dangerous, because there is an unseen world around us, inhabited by myriads of harmful bacteria, viruses, parasites and fungi. Their goal is to survive, feeding and multiplying. They often survive by feeding off our cells! Weakened immune system allows invaders to penetrate our body and poison our life.

Parasitic infection is a successful invasion of a host by an organism that uses the host for food and shelter. Parasites (in greek «parasitos» mean "dinner guest" from para "beside" + sitos "grain, meal") are organisms that live inside humans or other organisms who act as hosts. Small parasites – mostly protozoa and amoebae – are so tiny that they can only be seen with a microscope. Large parasites can be monstrous – sometimes even 9 meters long!

Parasites exist on our planet since ancient times. University of Colorado researchers have discovered what appears to be the first evidence of parasites in the gut contents of a dinosaur, indicating even the giants that roamed Earth 75 million years ago were beset by stomach worms.

According to a recent study, parasitic infections are widely spread in the world. Some scientists believe that approximately 85% of Northern Americans have at least one form of parasite.

Parasites can live inside the human body for years without making their presence known.

Some of the most common intestinal parasites include:

Pinworms – one of the most common parasitic infections. Pinworms reside in the colon, but lay eggs outside the body, usually near the anus, that causes severe itching.

The two most common tapeworms are Taenia solium (pork tapeworm) and Taenia saginata (beef tapeworm). Tapeworm infestation is caused by eating undercooked pork or beef. 
Protozoa (one-celled organisms) such as Giardia lamblia, Entamoeba histolytica, or Cryptosporidium are some of the most common and infectious parasites in the world, transmitted through contaminated food and water, or from one person to another.

Parasites are harmful to humans because they interfere with the normal physiological processes in the body; consume our food, that can cause malnutrition and vitamin and mineral deficiency; eat away body tissues and cells; produce toxic waste, and lower immunity.

The symptoms vary widely, but many parasitic infections cause intestinal problems such as diarrhea, intestinal obstruction, stomach pain, bloating, gas, loss of appetite, nausea, vomiting, fever, fatigue, headaches, muscle aches and pains, grinding teeth at night, skin rashes.

Parasitic infection frequently is undiagnosed because symptoms can be confused with a variety of conditions and diseases. And if parasite infection is not treated, parasites can remain in your system for decades and cause catastrophic disorders in the body.

There are simple ways to lessen the risk of parasitic infections: wash your hands often, especially after the contact with the animals; don’t eat undercooked meat, fish and poultry; when traveling, drink only bottled water; don’t eat food in the street; wash fruits thoroughly.

1. Schmeda-Hirschmann, G.; Papastergiou, F.Z. Naturforsch. 2003, 58c, 495.


2. Pinto CN, Dantas AP, De Moura KC, Emery FS, Polequevitch PF, Pinto MC, de Castro SL, Pinto AV. Chemical reactivity studies with naphthoquinones from Tabebuia with anti-trypanosomal efficacy. Arzneimittelforschung. 2000 Dec;50(12):1120-8.


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7. Mirelman D, Monheit D, Varon S. Inhibition of growth of Entamoeba histolytica by allicin, the active principle of garlic extract (Allium sativum). J Infect Dis 1987;156:243–4.


8. Bastidas CJ. Effect of ingested garlic on Necator americanus and Ancylostoma caninum. Am J Trop Med Hyg 1969;13:920–3.


9. Koch HP, Lawson LD, eds. Garlic: The Science and Therapeutic Application of Allium sativum L. and Related Species. Baltimore: Williams & Wilkins, 1996, 173–4.


10. Guarrera PM. J Ethnopharmacol 1999; 66(1-3): 183-192


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12. de Santana CF, de Almeida ER, Dos Santos ER, Souza IA. Action of Mentha crispa hydroethanolic extract in patients bearing intestinal protozoan. Fitoterapia 1992;63:409–10.


13. Keeney EL. Sodium caprylate: a new and effective treatment of moniliasis of the skin and mucous membrane. Bull Johns Hopkins Hosp 1946;78:333–9.


14. Neuhauser I, Gustus EL. Successful treatment of intestinal moniliasis with fatty acid resin complex. Arch Intern Med 1954;93:53–60.